Publications:


  1. Shah PK, Chyu KY, Fredrikson GN, Nilsson J. Immunomodulation of Atherosclerosis with a Vaccine. Nature Clinical Practice Cardiovascular Medicine, Dec 2005; 2(12):639-646.
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  2. Nilsson J, Hansson G, Shah PK. Immunomodulation of Atherosclerosis: Implications for Vaccine Development. Arterioscler Thromb Vasc Biol. 2005; 25:18-28.
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  3. Nilsson J, Hansson G. Autoimmunity in Atherosclerosis: A Protective Response Losing Control? J of Intern Med 2008; 263:464-478.
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  4. Sjögren P, Fredrikson GN, Samnegard A, Ericsson CG, Öhrvik J Fisher R, Nilsson J, Hamsten A.. High Plasma Concentrations of Autoantibodies against Native Peptide 210 of ApoB-100 are Related to Less Coronary Atherosclerosis and Lower Risk of Myocardial Infarction. Eur Heart J 2008; 29:2218-2226.
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  5. Fredrikson GN, Hedblad B, Berglund G, Alm R, Ares M, Cercek B, Chyu KY, Shah PK, Nilsson J. Identification of Immune Responses Against Aldehyde-Modified Peptide Sequences in Apo B Associated with Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2003; 23:872-878.
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  6. Fredrikson GN, Söderberg I, Lindholm M, Dimayuga P, Chyu Ky, Shah PK, Nilsson J. Inhibition of Atherosclerosis in Apo E-Null Mice by Immunization with Apo B-100 Peptide Sequences. Arterioscler Thromb Vasc Biol. 2003; 23:879-884.
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  7. Chyu KY, Zhao X, Reyes O, Babbidge S, Dimayuga P, Yano J, Cercek B, Fredrikson GN, Nilsson J, Shah PK. Immunization Using an Apo B-100 Related Epitope Reduces Atherosclerosis and Plaque Inflammation in Hypercholesterolemic Apo E (-/-) Mice. BBRC 2005; 338 (2005) 1982-1989.
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  8. Fredrikson GN, Hedblad B, Berglund G, Alm R, Nilsson JA, Schiopu A, Shah PK, Nilsson J. Association Between IgM Against Aldehyde-Modified Peptide in Apolipoprotein B-100 and Progression of Carotid Disease. Stroke 2007; 38:1495-1500.
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  9. Schiopu A, Frendeus B, Jansson B, Söderberg I, Ljungcrantz I, Araya Z, Shah PK, Carlsson R, Nilsson J, Fredrikson GN. Recombinant Antibodies to an Oxidized Low-Density Lipoprotein Epitope Induce Rapid Regression of Atherosclerosis in Apobec-1 -/- Low-Density Lipoprotein Receptor -/- Mice. J Am Coll Cardiol 2007; 50:2313-2318.
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  10. Fredrikson GN, Andersson L, Söderberg I, Dimayauga D, Chyu KY, Shah PK, Nilsson J. Atheroprotective Immunization with MDA-modified ApoB-100 Peptide Sequences is Associated with Activation of Th2 Specific Antibody Expression. Autoimmunity 2005; 38:17-179.
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  11. Fredrikson GN, Schiopu A, Berglund G, Alm R, Shah PK, Nilsson J. Autoantibody Against the Amino Acid Sequence 661-680 in apoB-100 is Associated with Decreased Carotid Stenosis and Cardiovascular Events. Atherosclerosis 2007; 194: e188-e192.
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  12. Fredrikson GN, Anand DV, Hopkins D, Corder R, Alm R, Bengtsson E, Shah PK, Lahiri A, Nilsson J. Associations between autoantibodies against apoB-100 peptides and vascular complications in patients with type 2 diabetes. Diabetologia 2009; 52:1426-1433.
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  13. Wigren M, Bengtsson D, Dunér P, Ljungcrantz I, Söderberg I, Björkbacka H, Fredrikson GN, Nilsson J. Evidence for a role of regulatory T cells in mediating the athero-protective effect of apolipoprotein B peptide vaccine. (in the press)
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  14. Fredrikson GN, Bjorkbacka H, Soderberg I, Ljungcrantz I, Nilsson J. Treatment with apo B peptide vaccines inhibits atherosclerosis in human apo B-100 transgenic mice without inducing an increase in peptide-specific antibodies. J Intern Med. 2008;264(6):563-570.
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  15. Hansson G, Nilsson J. Vaccination against atherosclerosis? Induction of athero-protective immunity. Semin Immunopathol 26 May 2009 (published online).
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  16. Xiaoning Zhao, Kuang-Yuh Chyu, Paul C Dimayuga, Juliana Yano, Xiaojun Li, Portia Trinidad, Jianchang Zhou, Wai Man Lio, Jonathan Kirzner, Lai F Chan, Bojan Cercek, and Prediman K Shah. Abstract 4908: Athero-protective Effects of Immunization With apoB-100 Related Peptide Vaccine in apoE–/– Mice is Associated With Enhanced CD8 Regulatory T Cell Response. Circulation 2009; 120: S1018.
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